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DURECT Corp
10240 Bubb Road
Phone: (408) 777-1417p:408 777-1417 CUPERTINO, CA  95014  United States Ticker: DRRXDRRX
Business Summary
DURECT Corporation is a late-stage biopharmaceutical company. The Company is engaged in the development of epigenetic therapies that target dysregulated deoxyribonucleic acid (DNA) methylation to transform the treatment of serious and life-threatening conditions, including acute organ injury. Its lead drug candidate, Larsucosterol binds to and inhibits the activity of DNA methyltransferases, epigenetic enzymes that are elevated and associated with hypermethylation found in alcoholic hepatitis (AH) patients. Larsucosterol is in clinical development for the potential treatment of AH, for which the FDA has granted a Fast Track and a Therapy designation, and metabolic dysfunction-associated steatohepatitis (MASH) is also being explored. Its commercial pharmaceutical product includes POSIMIR (bupivacaine solution) for infiltration use, a non-opioid analgesic utilizing the SABER platform technology. It has also completed Alcohol-Associated Hepatitis (AHFIRM) Phase 2b study.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-Yes---

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
9/30/202412/31/2023YesYes---

Industries
SIC Code Description
2834 Pharmaceutical preparations
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Independent Chairman of the Board Gail J.Maderis 67 3/17/2023 1/1/2021
President, Chief Executive Officer, Director James E.Brown 68 6/1/1998 6/1/1998
Chief Financial Officer, Company Secretary Timothy M.Papp 48 12/1/2022 7/1/2022
5 additional Officers and Directors records available in full report.

Business Names
Business Name
Absorbable Polymers International Corporation
DRRX
Southern BioSystems, Inc

General Information
Number of Employees: 45 (As of 11/11/2024)
Outstanding Shares: 31,041,981 (As of 11/11/2024)
Shareholders: 71
Stock Exchange: NASD
Federal Tax Id: 943297098
Fax Number: (408) 777-3577
Email Address: IR@durect.com


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Monday, January 27, 2025